Berberine. Another chemical compound in an endless series of plant-based substances that are expected to be a breakthrough in the strenuous, tedious, frustrating fight against extra pounds that vast masses of people fight every day.
Without giving anything to plants, they are too often required to do the impossible.
What do studies say about the effects of berberine on weight loss?
A systematic review of randomized controlled trials aimed at analyzing the effects of berberine on anthropometric parameters, CRP, and liver enzymes showed statistically significant reductions in berberine-related weight, BMI, waist circumference, and CRP, which may have played an indirect role in improving the clinical presentation of metabolic disorders. Berberine administration did not significantly affect AST and ALT levels.
A review of in vitro experimental studies in humans and animals that evaluated the efficacy of berberine and its impact on obesity and its associated metabolic consequences found, among other things, that:
- In preclinical models, berberine affects the intestinal microflora by reducing microbial diversity, starting with a dose of 100 mg / kg / day.
- It affects glucose levels by inhibiting beta-glycosidase at a dose of 200 mg / kg / day.
- It is effective for lowering lipid levels in rats, which therefore reduces the change in weight gain at a dose of 40 mg / kg to 380 mg / kg / day.
All of the above preclinical data were supported by human studies in which berberine can modulate gut microbial diversity at a dose of 500 mg / day. Berberine was found to have a beneficial effect on the regulation of cholesterol absorption genes at a daily dose of 300 mg in humans, and improved glucose storage at a daily dose of 1.0 g was also observed.
To sum it all up, the addition of berberine and the prospect of its potential effects looks pretty floral, doesn't it?
Not quite. Before visiting the pharmacy, you should learn a few additional information.
What are the risks of using berberine for weight loss?
First, the bioavailability of berberine is low, which means that you need to take high doses at the same time. This increases the risk of possible side effects. Second, in the studies used to draw conclusions, the first review used doses ranging from 300 mg to 1,500 mg per day, and the studies ranged in duration from a month to a year. This means about the same amount that the dosage adapted for us, we will have to turn out of the coffee grounds.
How does berberine affect weight loss?
As mentioned, there is some evidence of berberine's health benefits. This can help some metabolic processes and improve the overall functioning of the body. This does not mean that berberine is useless or has a completely neutral effect.
Summary of Weight Loss Information
The reality is that losing weight requires a balanced diet, regular physical activity, and a general approach to a healthy lifestyle.
There is no magic pill or super food (like berberine) that will solve all our problems. It just doesn't work that way. If you really want to lose pounds, it's best to focus on proven and scientifically proven methods.
A balanced diet, regular physical activity, and sufficient sleep are the main elements of a healthy lifestyle. Adding a little berberine to it doesn't hurt, but don't expect all your problems to disappear in one magical act.
Supplements containing berberine
Among the many supplements on the market designed to support health and control blood sugar levels, berberine stands out as the active ingredient. These additives are m.in. NuviaLab Sugar Control and Redusugar.
NuviaLab Sugar Control
Nuvialab Sugar Control is a drug designed to support blood sugar control, which is especially important in the context of the growing popularity of high-sugar foods and sugary drinks. NuviaLab Sugar Controlin addition to berberine, it also contains other ingredients such as bitter melon fruit extract, gurmaru leaf extract, or alpha-lipoic acid, which have documented effects for maintaining healthy blood sugar levels. Opinions about this supplement vary, but its composition and support in the scientific literature suggest that it can be a valuable addition to the diet of people who care about a healthy lifestyle.
The Redusugar supplement contains berberine, which, as mentioned earlier, has potential benefits in controlling blood sugar levels and may support metabolic processes. Other than Berberine, Redusugar also contains other natural plant extracts such as ginger and cinnamon. Users of this supplement often highlight its benefits, such as lowering morning blood sugar levels and overall well-being. If you are interested in supporting your health and want to take advantage of the potential benefits of berberine, it is worth paying attention to supplements such as Redusugar.
- Asbaghi, Omid, et al. „The effect of berberine supplementation on obesity parameters, inflammation and liver function enzymes: A systematic review and meta-analysis of randomized controlled trials.” Clinical nutrition ESPEN 38 (2020): 43-49.
- Ilyas, Zahra, et al. „The effect of Berberine on weight loss in order to prevent obesity: A systematic review.” Biomedicine & Pharmacotherapy 127 (2020): 110137.